Renew my subscription. Davis's Drug Guide. Tags Type your tag names separated by a space and hit enter. Explore these free sample topics: hydroxychloroquine azithromycin metoprolol Pediatric Dosage Calculations. To hear audio pronunciation of this topic, purchase a subscription or log in. Citation Vallerand, April Hazard. Davis Company, Davis Company; Accessed November 12, Vallerand, A.
In Davis's Drug Guide 16th edition. Davis Company. In: Davis's Drug Guide. Each tablet yields approximately mg of phosphorus, mg of sodium H2O, Molecular Weight: Inactive Ingredients: Lactose monohydrate, povidone, white coating hydroxypropyl methylcellulose, titanium dioxide, maltodextrin, triacetin, glycerol triacetate, polyethylene glycol, sodium citrate, and stearic acid , sodium starch glycolate, and magnesium stearate.
Phosphorus has a number of important functions in the biochemistry of the body. The bulk of the body's phosphorus is located in the bones, where it plays a key role in osteoblastic and osteoclastic activities. Enzymatically catalyzed phosphate-transfer reactions are numerous and vital in the metabolism of carbohydrate, lipid and protein, and a proper concentration of the anion is of primary importance in assuring an orderly biochemical sequence.
In addition, phosphorus plays an important role in modifying steady-state tissue concentrations of calcium. Phosphate ions are important buffers of the intracellular fluid, and also play a primary role in the renal excretion of hydrogen ion. Oral administration of inorganic phosphates increases serum phosphate levels. Phosphates lower urinary calcium levels in idiopathic hypercalciuria.
In general, in adults, about two thirds of the ingested phosphate is absorbed from the bowel, most of which is rapidly excreted into the urine. Recommended Daily Allowance U. RDA of phosphorus for adul t s and children over 4 years of age. This product contains potassium and sodium and should be used with caution if regulation of these elements is desired. Occasionally, some individuals may experience a mild laxative effect during the first few days of phosphate therapy.
If laxation persists to an unpleasant degree, reduce the daily dosage until this effect subsides or, if necessary, discontinue the use of this product. Caution should be exercised when prescribing this product in the following conditions: Cardiac disease particularly in digitalized patients ; severe adrenal insufficiency Addison's disease ; acute dehydration; severe renal insufficiency; renal function impairment or chronic renal disease; extensive tissue breakdown such as severe burns ; myotonia congenita; cardiac failure; cirrhosis of the liver or severe hepatic disease; peripheral or pulmonary edema; hypernatremia; hypertension; toxemia of pregnancy; hypoparathyroidism; and acute pancreatitis.
Rickets may benefit from phosphate therapy, but caution should be exercised. High serum phosphate levels may increase the incidence of extra-skeletal calcification. Patients with kidney stones may pass old stones when phosphate therapy is started and should be warned of this possibility.
Patients should be advised to avoid the use of antacids containing aluminum, magnesium, or calcium which may prevent the absorption of phosphate. Potassium and Sodium Phosphates [Internet]. In: Davis's Drug Guide. Your free 1 year of online access expired. Log in to Harriet Lane. Forgot Your Password? Enter your username below and we'll send you an email explaining how to change your password.
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